Reserve CBD+CBN+CBC+CBG Tincture 1:1:1:1
Reserve CBD+CBN+CBC+CBG Tincture 1:1:1:1Add Review
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The Keylife Reserve Tincture is the culmination of our hard work and development, a premiere product featuring four major cannabinoids... in an equal 1:1:1:1 ratio of CBD, CBN, CBC, and CBG. Our reserve tincture is made using only broad-spectrum cannabinoids, ensuring it contains zero THC and is manufactured entirely within the U.S. from the farm to the final bottled product.Grown using all-organic, non-GMO cannabis, we have implemented strict quality-control practices to ensure that our plants are kept free of all pesticides and heavy metals. We also use third-party lab testing to ensure that all of our products are accurate in their label claims and ingredient contents, with results published on the website. Lastly, all of our tinctures are vegan-friendly and gluten-free, so they can fit into your ever-evolving lifestyle or diet choices.
If you are not 100% satisfied with our product, you can contact our sales team and get a full refund within 7 days of your purchase.
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The Keylife Reserve Tincture is the culmination of all of our research, farming, and testing, focused on producing one of the most all-encompassing levels of cannabinoids possible, allowing you to reap the benefits to your health in as many ways as possible.
Our tincture contains at least 250mg of broad-spectrum CBD, CBG, CBC, and CBN each in a 1:1:1:1 ratio, meaning you receive a significant quantity of each cannabinoid, rather than a disproportional blend comprised predominantly of CBD with lesser amounts of other cannabinoids blended in. Our Reserve Tincture is a broad-spectrum product, meaning it contains zero traces of any THC.
We create all of our Keylife CBD products with only the finest non-GMO cannabis plants, grown entirely within the U.S. using organic farming techniques, free from all pesticides and heavy metals.
Upon harvesting the cannabis, we begin an extraction process to pull the required cannabinoids from our plants. Extraction is completed by sending super-critical CO2 through the harvested and trimmed plant matter to extract the cannabinoids from the terpenes, lipid molecules, and other plant compounds contained within the trimmings. Super-critical CO2 simply means that the CO2 is both extremely cold and high in pressure (approximately -69º F and 75 pounds PSI)3, allowing it to exist as both a gas and liquid simultaneously, which helps it pass through the plant material more easily and with greater impact on the contents. The CO2 acts as a solvent on the plant matter, helping it to breakdown, before being removed altogether, leaving behind a full spectrum extract4 which is then further processed with an additional step in order to become the broad spectrum extract that we seek. Utilizing a CO2 process is costly, but it is a safer method of extraction and one that generally yields both the highest volume and purest quality of the product.
The next step is to send the broad spectrum extract along for short-path distillation, which eliminates all traces of THC and any other unwanted substances, resulting in a broad-spectrum product. Remember, broad-spectrum tinctures contain 0% THC content. Eventually, we are left with only the CBD, CBC, CBN, and CBG cannabinoids we seek, which we then combine with our cold-pressed hemp seed oil. Before we ship the final tincture off to Florida for bottling and packaging, we conduct individual batch, third-party lab testing to ensure that all of our products are accurate for cannabinoid content and are completely free of all additives or sweeteners. All lab tests are publicly published and are both listed on our website and available upon request.
Each 30mL bottle of Keylife Reserve CBD + CBN + CBC + CBG 1:1:1:1 Tincture comes in a 1000mg strength and features at least 250mg of each cannabinoid. In order to ensure the maximum levels of purity and potency, we only offer our Reserve Tincture in our unflavored “Natural” option.
There are numerous cannabinoid products on the market these days, from edibles to salves, sprays, vapeables, smokables, bath products, and even pet treats, it seems the options are endless. If you are looking for a product that is simple to use and rapid in its effects, then tinctures might be the right choice for you. Tinctures also have a high level of bioavailability or the rate and volume of how fast a drug is taken into your system. Tinctures are applied sublingually, or under the tongue, so that they can be absorbed into your vascular system quickly through your capillaries. Sublingual applications tend to have a 13% to 19% bioavailability rate (or how much and how fast a drug is absorbed into your system), though this can be as high as 35% in some forms. Sublingual dosing provides a higher rate of bioavailability than simple oral dosing, so to ensure maximum efficacy always keep the tincture under your tongue for anywhere from 30 to 60 seconds. If you simply swallow a tincture without sublingual application first, you’ll still reap some benefits of the CBD, but the bioavailability could be reduced to as little as 6%.5
Below are some of the ways that the CBG, CBC, CBN, and CBD cannabinoids contained within our Reserve Tincture could potentially benefit your health:
Cannabigerol, or CBG as its commonly referred to, has a variety of potential medical applications:
– Appetite stimulant: Studies in rats found that CBG had an impact “by reducing latency to feed and increasing meal frequency,” meaning that the rats become more hungry, more frequently. This implies that CBG may be beneficial for those suffering from loss of appetite, a common side-effect in those undergoing chemotherapy treatment.6
– Antibiotic treatments: Various studies have shown the potency of cannabinoids when it comes to their effects as potential antibiotic treatments. A 2008 study on CBG found that it “showed potent activity against a variety of methicillin-resistant Staphylococcus aureus (MRSA) strains.”7 In addition, a study conducted by the Centre for Superbug Solutions at the Institute for Molecular Bioscience at the University of Queensland in Australia also found that CBD is an incredibly effective alternative to traditional antibiotics. When used as a treatment against staphylococcus and streptococcus, CBD worked faster than commonly prescribed antibiotics. The center’s senior research officer, Mark Blaskovich, Ph.D., was quoted as saying, “We looked at how quickly the CBD killed the bacteria, It’s quite fast, within 3 hours, which is pretty good, Vancomycin (Vancocin) kills over 6 to 8 hours.” Blaskovich concluded that “In every case, CBD had a very similar potency to that of common antibiotics.”1 These studies seem to indicate that both CBD and CBG have the potential to replace current antibiotic applications, with the possibility of expedited improvement with fewer side effects when compared with traditionally prescribed drugs.
– Neurological applications: CBG has been shown to assist in the antioxidant processes in the brain and in helping to prevent the early deterioration of nerve cells that can eventually lead to the onset of such conditions as Huntington’s disease.8
– Carcinogenesis inhibition: One of the most fascinating, and potentially impactful, medical studies on the effects of CBG, is on its ability to act as a possible inhibitor of carcinogenesis, or the process by which the body produces cancer cells. A 2014 study found that CBG was shown to slow the rate of carcinogenesis in colon cancer sufferers.9
CBC or cannabichromene is one of the most abundant cannabinoids but also one of the least researched. CBC is created from the same acid that produces CBD and THC: cannabigerolic acid (CBGA). CBGA is also referred to as the “stem cell” cannabinoid due to its ability to transform via enzymes into a variety of compounds such as CBDA, THCA, and CBCA, which are all precursors of three of the main cannabinoids. Unlike most cannabinoids, CBC binds better to the TRPV1 and TRPA1 receptors in the ECS, rather than the more commonly used CB1 and CB2 receptors.10
Initial research has shown that CBC may help with the following issues:
– Chronic pain relief: Studies with rats have shown great potential for CBC as an analgesic, especially in relation to the symptoms of osteoarthritis. This also means CBC may be a possible alternative to traditional opioid or steroid treatments that are usually prescribed for pain management.11
– Neural regeneration: CBC has been shown to promote neurogenesis or the growth/repair of the brain. In patients with Alzheimer’s and dementia, this naturally occurring and lifelong process is interrupted. A 2013 study12 found that CBC increased the viability of neural stem cells in adult mice, meaning the cannabinoids “improved their function.”10
– Antibacterial agent: Early research indicates a propensity toward antibacterial applications. A study cited by the National Center for Biotechnology Information showed a positive response to “gram-positive, gram-negative and acid-fast bacteria,” showing “antibacterial activity was strong, and the antifungal activity was mild to moderate.” Applications such as the treatment of MRSA (Methicillin-Resistant Staphylococcus Aureus), the notoriously hard-to-treat bacterial infection, have been suggested accordingly.13
– Anti-depressant: A study from the University of Mississippi in 2010 found that rats administered CBC “achieved better results in stress tests. It is believed that chronic stress is one of the main triggers associated with depression. In short, the better you adapt to stress, the less likely you are to become depressed.”10,14
– Skincare and acne: A 2016 study found that “CBC was a powerful inhibitor of acne, a disease where excessive levels of sebum production and inflammation of the sebaceous gland are the main causes.”10 CBC helps reduce the rate at which the body produces these excessive levels of oil, helping keep skin free of acne breakouts.15
Cannabinol or CBN for short is generated as the cannabis plant ages. Exposure to sunlight, air, and heat, in combination with enzyme interaction ultimately turns cannabigerolic acid (CBGA) within the plant into CBN.16
Possible health applications for CBN may include the following:
– Appetite stimulant: In a lab test conducted on rats in 2012, scientists discovered that “CBN was found to stimulate appetite. It increased food consumption and increased appetitive and consummatory behaviors for the duration of the test.”16,17 Possible applications for such treatments include assisting patients undergoing chemotherapy or those who suffer from loss of appetite either due to disease or treatment side effects.
– Analgesic and pain relief: “CBN influences the activity of capsaicin-sensitive neurons, which play a role in pain signaling and pain perception.”16,18 A 2019 study discovered that the pairing of CBD and CBN may be “effective at relieving myofascial pain, which is often caused by physical injury or overuse of certain muscles.”16 According to the study, “These results suggest that peripheral application of these non-psychoactive cannabinoids may provide analgesic relief for chronic muscle pain disorders such as temporomandibular disorders and fibromyalgia without central side effects.”19
– Skin conditions: CBN has been “found to reduce the proliferation of keratinocyte, a skin cell that produces keratin. Overproduction of keratinocytes is at the heart of the skin lesions common in psoriasis. Combined with its anti-inflammatory properties, CBN could be good news for psoriasis sufferers.”16,20
– Glaucoma: One of the conditions most famously treated with cannabis over the years is glaucoma, which the American Academy of Ophthalmology describes as “a disease that damages your eye’s optic nerve … when fluid builds up in the front part of your eye.”21 This buildup of pressure and damage to the optic nerve can potentially lead to a loss of vision and even blindness. CBN seems to influence lowering the internal pressure of the eyes, preventing the buildup of this fluid.22
– Cancer treatment and tumor growth inhibition: A lab study on mice from 1975 involving the paired administering of CBN with THC “was found to inhibit tumor growth in a particular type of lung cancer. The mice that received CBN also had a longer average survival time than those that did not.”16, 23
Cannabidiol or CBD is the most widely researched and publicly discussed of all the cannabinoids beyond THC. Products have emerged throughout the market over the years claiming the various supposed benefits of CBD and increasingly, science is finding there is truth in many of those claims.
Health.harvard.edu states that CBD has been suggested “for a wide variety of health issues,” so here are some of the potential ways in which this amazing cannabinoid may benefit you:
– The prevention of seizures from epilepsy: specifically, childhood epilepsy and such debilitating disorders as Dravet Syndrome and Lennox-Gastaut syndrome (LGS)
– Treatment for anxiety and depression: Cannabinoids have been shown in lab tests to reduce anxiety, which is the leading contributing factor in suffering from depression. An interesting note is that CBD has been proven to reduce anxiety across all types of individuals, regardless of whether they suffer from some form of anxiety disorder or not.24
– Sleep regulation and insomnia: Early research from the National Center for PTSD and Palo Alto University shows that CBD may have “therapeutic potential for the treatment of insomnia,” and “may hold promise for REM sleep behavior disorder and excessive daytime sleepiness.”25
– The potential to inhibit inflammatory and neuropathic chronic pain (such as symptoms shown in arthritis sufferers)26
– Relief from symptoms caused by Multiple sclerosis: CBD is effective in improving pain and muscle tightness in sufferers of MS27, allowing for an improved quality of life.
Keylife CBD has gone to great lengths, whether it be in farming techniques, conducting research, investing in technology, or in offering complete transparency in lab testing, to ensure that no corners are cut, no misleading claims are ever made, and that only the highest quality, all-natural CBD products end up in your hands. Try our Keylife Reserve CBD + CBN + CBC + CBG 1:1:1:1 Tincture today and see how it can impact your life in a positive and beneficial way.
FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE: These statements have not been evaluated by the FDA and are not intended to diagnose, treat, or cure any disease. Always check with your physician before starting a new dietary supplement program.
- Appendino G, Gibbons S, Giana A, Pagani A, Grassi G, Stavri M, Smith E, Rahman MM. “Antibacterial cannabinoids from Cannabis sativa: a structure-activity study.” National Library of Medicine, National Center for Biotechnology Information, Journal of Natural Products, August 2008.
- Jose A, Thomas L, Baburaj G, Munisamy M, Rao M. “Cannabinoids as an Alternative Option for Conventional Analgesics in Cancer Pain Management: A Pharmacogenomics Perspective.” US National Library of Medicine, National Institutes of Health, Indian Journal of Palliative Care, January 2020.
- “The Benefits of CO2 Extraction for Making CBD Oil.” PureKana, May 2017.
- “How is CBD Oil Made?” Echo Connection, July 2017.
- “CBD and Bioavailability.” CBD Awareness Project, July 2019.
- Brierley DI, Samuels J, Duncan M, Whalley BJ, Williams CM. “Cannabigerol is a novel, well-tolerated appetite stimulant in pre-satiated rats.” National Library of Medicine, National Center for Biotechnology Information, Psychopharmacology, August 2016.
- Doheny K. “CBD as a Superbug Antibiotic?” WebMD Health News, June 2019.
- Valdeolivas S, Navarrete C, Cantarero I, Bellido ML, Muñoz E, Sagredo O. “Neuroprotective properties of cannabigerol in Huntington’s disease: studies in R6/2 mice and 3-nitropropionate-lesioned mice.” National Library of Medicine, National Center for Biotechnology Information, Neurotherapeutics, January 2015.
- Borrelli F, Pagano E, Romano B, Panzera S, Maiello F, Coppola D, De Petrocellis L, Buono L, Orlando P, Izzo AA. “Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid.” National Library of Medicine, National Center for Biotechnology Information, Carcinogenesis, December 2014.
- Civantos D. “What is CBC and why is it a cannabinoid with great medicinal potential?” Dinafem Seeds, March 2019.
- Maione S, Piscitelli F, Gatta L, Vita D, De Petrocellis L, Palazzo E, De Novellis V, Di Marzo V. “Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action.” National Library of Medicine, National Center for Biotechnology Information, British Journal of Pharmacology, February 2011.
- Shinjyo N, Di Marzo V. “The effect of cannabichromene on adult neural stem/progenitor cells.” Science Direct, Neurochemistry International, November 2013.
- Turner CE, Elsohly MA. “Biological activity of cannabichromene, its homologs and isomers.” National Library of Medicine, National Center for Biotechnology Information, The Journal of Clinical Pharmacology, September 1981.
- El-Alfy A, Ivey K, Robinson K, Ahmed S, Radwan M, Slade D, Khan I, ElSohly M, Ross S. “Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L.” National Library of Medicine, National Center for Biotechnology Information, Pharmacology Biochemistry and Behavior, June 2010.
- Oláh A, Markovics A, Szabó-Papp J, Szabó PT, Stott C, Zouboulis CC, Bíró T. “Differential effectiveness of selected non-psychotropic phytocannabinoids on human sebocyte functions implicates their introduction in dry/seborrhoeic skin and acne treatment.” National Library of Medicine, National Center for Biotechnology Information, Experimental Dermatology, September 2016.
- Brett J. “What Is CBN?” CBD Oil Review, November 2020.
- Farrimond JA, Whalley BJ, Williams CM. “Cannabinol and cannabidiol exert opposing effects on rat feeding patterns.” National Library of Medicine, National Center for Biotechnology Information, Psychopharmacology, April 2012.
- Zygmunt PM, Andersson DA, Högestätt ED. “Δ9-Tetrahydrocannabinol and Cannabinol Activate Capsaicin-Sensitive Sensory Nerves via a CB1 and CB2 Cannabinoid Receptor-Independent Mechanism.” Journal of Neuroscience, June 2002.
- Wong H, Cairns BE. “Cannabidiol, cannabinol and their combinations act as peripheral analgesics in a rat model of myofascial pain.” National Library of Medicine, National Center for Biotechnology Information, Archives of Oral Biology, August 2019.
- Wilkinson JD, Williamson EM. “Cannabinoids inhibit human keratinocyte proliferation through a non-CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis.” National Library of Medicine, National Center for Biotechnology Information, Journal of Dermatological Science, February 2007.
- Boyd K, McKinney JK. “What Is Glaucoma?” American Academy of Opthalmology, October 2020.
- Kogan NM, Mechoulam R. “Cannabinoids in health and disease.” US National Library of Medicine, National Institutes of Health, Dialogues in Clinical Neuroscience, December 2007.
- Munson AE, Harris LS, Friedman MA, Dewey WL, Carchman RA. “Antineoplastic activity of cannabinoids.” National Library of Medicine, National Center for Biotechnology Information, Journal of the National Cancer Institute, September 1975.
- Stoner SA. “Effects of Marijuana on Mental Health: Anxiety Disorders.” University of Washington, June 2017.
- Babson KA, Sottile J, Morabito, D. “Cannabis, Cannabinoids, and Sleep: a Review of the Literature.” National Library of Medicine, National Center for Biotechnology Information, Current Psychiatry Reports, April 2017.
- Grinspoon P. “Cannabidiol (CBD) — what we know and what we don’t.” Harvard Medical School, August 2018.
- “Cannabidiol (Cbd) OTHER NAMES(S): 2-[(1R,6R)-3-Methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol, CBD.” WebMD, Therapeutic Research Faculty, 2018.
Our Keylife Reserve Tincture was designed with maximum efficacy in mind. By combining four of the main cannabinoids found within the cannabis plant, we hope to mimic the “entourage effect,” where the sum of the cannabinoids is greater than the whole. This commonly accepted belief dictates that cannabinoids can work synergistically to magnify their effects when combined, versus a lessened impact when dosed individually.
Our Reserve Tincture is therefore manufactured entirely within the U.S. using four broad-spectrum cannabinoids: Cannabigerol (CBG), cannabinol (CBN), cannabichromene (CBC), and cannabidiol (CBD), all in a 1:1:1:1 ratio of 250mg each in every 30ml bottle, for a combined total strength of 1000mg of cannabinoids. We extract these cannabinoids from our own organically grown, non-GMO cannabis plants, ensuring that no pesticides or heavy metals are used during the farming process. We also conduct thorough third-party lab testing of all of our products so you can ensure that every one of our products lives up to their label claims.
Every bottle of the Reserve Tincture comes in a 30ml size and a 1000mg strength level. Due to the desire to keep the tincture as pure and as potent as possible, it is only available in our unflavored “Natural” option.
The Keylife Reserve CBD + CBN + CBG + CBC 1:1:1:1 Tincture contains the following ingredients:
Broad Spectrum CBD, CBN, CBG, and CBC – Extracted from our own high-yield organic cannabis plants, all of our cannabinoids in the reserve tincture are considered “Broad Spectrum” meaning they contain absolutely no traces of THC. Every bottle contains at least 250mg of each cannabinoid in a perfect 1:1:1:1 ratio, meaning you receive equal parts of each one, not just some trace amounts added to a standard CBD tincture. While this results in a costlier product, we feel it offers the maximum possible reach on as many areas of your health and well-being as possible.
Cold-Pressed Hemp Seed Oil – In order to effectively bind to the internal receptors that make up the endocannabinoid system or self-regulating system within our bodies, cannabinoids must be paired with a lipid or fat molecule. The traditional choice for cannabinoid tincture manufacturers has been MCT or coconut oil, it is affordable, readily available, and relatively easily absorbed into our systems. At Keylife CBD we realized that this was really a missed opportunity though, by alternatively using oil created from the hemp seeds of the cannabis plant, we not only waste less of the harvested material, but it also allows us to squeeze in a few more cannabinoids and potential health benefits to you. Cold-pressed Hemp Seed Oil is more expensive to produce, but we think it yields a tastier and more beneficial product to you, offering a high nutritional makeup loaded with essential omega fatty acids.
All four cannabinoids within our Keylife CBD Reserve Tincture are potent antibacterial agents, showing a strong propensity for defeating gram-positive and gram-negative bacterial infections.1
CBD can regulate our circadian rhythm, the natural internal clock that determines how fast and for how long we sleep. CBD can also minimize the effects of distractions that may prematurely awaken us.
CBN helps promote homeostasis within the eyes by regulating their internal pressure and preventing a build-up of fluid that can eventually lead to reduced vision or issues such as glaucoma.
Both CBG and CBN have shown an ability to potentially impact and reduce the number, and rate of growth, of new cancer or tumor cells in the body.
CBN, CBC, and CBD have shown promise in helping to mitigate chronic inflammatory and neuropathic pain by activating receptors within the central nervous system and blocking the production of pain and inflammatory mediators.2
Cannabinoids can assist the brain in a variety of ways, either by helping to maintain homeostasis or by preventing the early onset of neurodegenerative issues. CBC shows signs of potential neuroregenesis in the brain by increasing the viability of neural stem cells. CBD can promote an antioxidant environment in the brain by preventing the formation of free radical agents.
Cannabinoids as a whole can influence the receptors involved in emotional responses by mimicking our own, naturally produced endocannabinoids. CBG can act on specific areas of the brain to help regulate serotonin and GABA uptake, which then helps mediate synaptic activity in the brain. CBD influences neural receptors in the brain, assisting in maintaining normal brain chemistry and the regulation of emotions, potentially reducing stress, which is the leading contributing factor in emotional issues such as depression.
Prevention of Seizures
The most well-known application for cannabinoids is in the prevention and alleviation of seizures in those affected by conditions such as epilepsy. CBD has been shown to effectively reduce the level of severity and number of instances of seizures occurring.
CBG, CBC, and CBD all offer anti-inflammatory relief that can potentially reduce joint and muscle swelling and stiffness, improving flexibility, range of motion, and mobility.
Tinctures are administered orally, specifically sublingually, meaning they are placed under the tongue. Thanks to the numerous small veins under the tongue, referred to as capillaries, CBD and other cannabinoids can be absorbed quickly and efficiently into the bloodstream. Ensuring you receive the most cannabinoids possible in the shortest amount of time possible.
1) Shake tincture gently.
2) Remove the child-safety cap with a built-in pipette.
3) Squeeze the bulb of the pipette to fill one full dropper worth of liquid into the pipette, this should be approximately 20 drops or 1ml of liquid.
4) Drip and hold tincture under the tongue for 15 to 20 seconds before swallowing any remaining liquid.
5) Always wait approximately three hours after the initial dose to see how the level of CBD and other cannabinoids affect you.
6) Administer each dose, one to three times a day as needed.
7) Upon dosing, always store your tinctures in a cool, dark location, out of the reach of children and pets.
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